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[注意力缺陷多动障碍合并焦虑症:药物治疗选择]

[Attention deficit hyperactivity disorder with comorbid anxiety disorders: pharmacotherapy options].

作者信息

Zavadenko N N, Solomasova A A

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2012;112(8):44-8.

Abstract

Comorbid anxiety disorders are observed in many patients with attention deficit hyperactivity disorder (ADHD): 25-33% compared to 6-10% in pediatric population. Therapeutic effects of Adaptol have been studied, indicated for children and adolescents with ADHD as monotherapy, in dosages of 25-35 mg/kg for 1-3 months. The positive influence of Adaptol on the core symptoms of ADHD was confirmed: reduction of hyperactivity and impulsivity was registered after 1st month, while clinical manifestations of the attention deficit were decreased on the 2nd-3rd months of the treatment. Anxiolytic activity became apparent from the 1st month and continued to increase on the 2nd-3rd months of the treatment. Simultaneously significant reduction of the oppositional-defiant disorder manifestations were observed.

摘要

许多注意力缺陷多动障碍(ADHD)患者同时存在焦虑症:ADHD患者中患焦虑症的比例为25%-33%,而儿科人群中这一比例为6%-10%。已经对阿得尔(Adaptol)的治疗效果进行了研究,它适用于患有ADHD的儿童和青少年,作为单一疗法,剂量为25-35毫克/千克,疗程为1-3个月。阿得尔对ADHD核心症状的积极影响得到了证实:第一个月后多动和冲动症状减轻,而注意力缺陷的临床表现则在治疗的第二至第三个月有所减少。抗焦虑活性从第一个月开始显现,并在治疗的第二至第三个月持续增强。同时,对立违抗障碍的表现也显著减少。

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