Department of Radiology, Boston University School of Medicine, Boston, MA, USA.
AJR Am J Roentgenol. 2012 Nov;199(5):952-67. doi: 10.2214/AJR.11.8182.
Pancreatic cancer continues to have a poor prognosis despite impressive improvements in the outcomes of many other types of cancer, often because most pancreatic neoplasms are found to be unresectable at diagnosis. The purpose of this review is to provide an overview of pancreatic cancer and the role of modern imaging in its diagnosis and management with an emphasis on (18)F-FDG PET/CT fusion imaging.
Multimodality imaging is critical in the diagnosis and management of pancreatic cancer. PET/CT is increasingly viewed as a useful, accurate, and cost-effective modality in diagnosing and managing pancreatic cancer, but further studies are warranted. Early data suggest that contrast-enhanced PET/CT performed with modern PET/CT scanners yields high-resolution anatomic information for surgical and radiotherapeutic planning and functional information for whole-body staging in the care of patients with this disease.
尽管许多其他类型癌症的治疗效果显著改善,但胰腺癌的预后仍然较差,这通常是因为大多数胰腺肿瘤在诊断时已无法切除。本综述的目的是概述胰腺癌以及现代影像学在其诊断和治疗中的作用,重点介绍 (18)F-FDG PET/CT 融合成像。
多模态成像在胰腺癌的诊断和管理中至关重要。PET/CT 被越来越多地视为诊断和管理胰腺癌的一种有用、准确且具有成本效益的方法,但仍需要进一步的研究。早期数据表明,使用现代 PET/CT 扫描仪进行增强对比度的 PET/CT 可为手术和放射治疗计划提供高分辨率解剖学信息,并为该疾病患者的全身分期提供功能信息。