Nakamura Reid K, Zimmerman Sarah A, Lange Ashley J, Lesser Michael B
Advanced Veterinary Care Center, Lawndale, CA, USA.
J Vet Cardiol. 2012 Dec;14(4):531-6. doi: 10.1016/j.jvc.2012.04.002. Epub 2012 Oct 24.
A 4-year-old male castrated Borzoi dog presented on referral for evaluation of pleural effusion, ventricular arrhythmias, and suspected dilated cardiomyopathy. Echocardiogram identified several masses along the chordae tendineae, as well as a long the annulus of the mitral valve. A blood culture was positive for methicillin resistant Staphylococcus lugdunensis. The dog was also positive for Bartonella DNA on PCR testing. Aggressive antibiotic therapy was instituted. However, the dog continued to have recurrent pleural effusion and progressive azotemia. The dog was euthanized 39 days after diagnosis. Necropsy confirmed the presence of intracardiac abscesses, thrombosis and endocarditis. S. lugdunensis is a recently identified rare cause of endocarditis in humans characterized by intracardiac abscess formation, highly destructive valvular lesions preferentially affecting the mitral valve and a high mortality rate. This is the first reported case of S. lugdunensis isolation in a dog with endocarditis.
一只4岁去势的俄罗斯猎狼犬因胸腔积液、室性心律失常和疑似扩张型心肌病转诊来院评估。超声心动图检查发现沿腱索以及二尖瓣瓣环有多个肿块。血培养结果显示耐甲氧西林的路邓葡萄球菌呈阳性。该犬经聚合酶链反应检测巴尔通体DNA也呈阳性。遂开始积极的抗生素治疗。然而，该犬仍反复出现胸腔积液并伴有进行性氮质血症。诊断39天后对其实施安乐死。尸检证实存在心内脓肿、血栓形成和心内膜炎。路邓葡萄球菌是最近发现的人类心内膜炎的罕见病因，其特征为心内脓肿形成、高度破坏性的瓣膜病变，优先累及二尖瓣且死亡率高。这是首次报道在患有心内膜炎的犬中分离出路邓葡萄球菌的病例。
