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[外科重症医学中的医院感染。一项5年前瞻性研究的结果]

[Nosocomial infections in surgical intensive medicine. Results of a 5-year prospective study].

作者信息

Hartenauer U, Diemer W, Gähler R, Ritzerfeld W

机构信息

Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Münster.

出版信息

Anasth Intensivther Notfallmed. 1990 Feb;25(1):93-101.

PMID:2309997
Abstract

All the ICU patients were continuously studied during the first quarter of 5 consecutive years for infections according to a standard protocol. The investigators--the infection control officer and a well-trained infection control nurse--decided if the patient was infected by referring to medical and nursing record, temperature charts, laboratory and x-ray reports and, where necessary, by clinical examination. Definitions and criteria for infections comply with the CDC and the algorithms of the Senic Project. Only the first quarter of each year from 1980-1984 was analysed. The first quarter of 1980 was analysed retrospectively, the following years were examined prospectively. In 1984 a new ICU (ICU I) in addition to the old ICU (ICU II) was opened. The two ICUs differ in building construction but have similar patients, nursing staff and medical standards. The frequency of nosocomial infection was not affected by the different building constructions. The number of patients surveyed was 1009, 60% were males and 40% females. The average age was 45.5 years and the average period of stay about 4 days. 733 patients (72.6%) were intubated and artificially ventilated for 3 days. A fatal outcome resulted in 13.2% of all patients. 1129 nosocomial infections were registered in 311 patients, which means an infection rate of 32.8%. The most frequent nosocomial infections were those of the respiratory tract. Wound infections developed in 16.6%. The urinary tract was affected in 8.8%. Nosocomial septicaemias were observed in 8.7%. Catheter-associated infections were noticed in 6.7% of the patients. A fatal outcome resulted in 26% of the patients with nosocomial infections and in 6.9% of the non-infected patients, respectively.

摘要

按照标准方案,在连续5年的第一季度对所有重症监护病房(ICU)患者进行了关于感染情况的持续研究。研究人员——感染控制官员和一名训练有素的感染控制护士——通过查阅医疗和护理记录、体温图表、实验室及X光报告,并在必要时进行临床检查,来判定患者是否受到感染。感染的定义和标准符合美国疾病控制与预防中心(CDC)及卫生保健相关感染国家监测(Senic)项目的算法。仅对1980年至1984年每年的第一季度进行了分析。1980年第一季度进行了回顾性分析,随后几年进行了前瞻性研究。1984年,除了旧的ICU(ICU II)外,新的ICU(ICU I)开放。两个ICU在建筑结构上有所不同,但患者、护理人员和医疗标准相似。不同的建筑结构并未影响医院感染的发生率。接受调查的患者有1009人,其中60%为男性,40%为女性。平均年龄为45.5岁,平均住院时间约为4天。733名患者(72.6%)接受了插管并进行了3天的人工通气。所有患者中有13.2%出现了致命结局。在311名患者中记录到1129例医院感染,这意味着感染率为32.8%。最常见的医院感染是呼吸道感染。伤口感染发生率为16.6%。泌尿道感染发生率为8.8%。医院败血症发生率为8.7%。6.7%的患者出现了与导管相关的感染。医院感染患者中有26%出现了致命结局,未感染患者中的这一比例为6.9%。

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