Lee Young Jin, Jung Eun Joo, Lee Seung Heon, Lee Young-Min, Kim Bomi, Choi Seok Jin, Jeong Dae Hoon, Lee Hyun-Kyung
Division of Pulmonology, Department of Internal Medicine, Pusan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Tuberc Respir Dis (Seoul). 2012 Jul;73(1):56-60. doi: 10.4046/trd.2012.73.1.56. Epub 2012 Jul 31.
A patient who has multiple lung masses with a history of malignancy in organs other than the lung is more likely to be diagnosed with metastatic rather than primary lung cancer. Rarely, metastatic cancer can coexist with primary. We experienced a case of concurrent diagnosis of primary small cell lung cancer and pulmonary metastasis of uterine malignant mixed Müllerian tumor (MMMT). The patient was a 52-year-old female with femur fracture and multiple lung masses with a history of an operation for uterine MMMT. The small cell lung cancer was diagnosed by bronchoscopic biopsy. The central lung mass decreased after chemotherapy for small cell lung cancer but multiple peripheral masses increased. A percutaneous biopsy for one of peripheral masses revealed metastatic uterine MMMT. We suggest that we have to consider the possible presence of concomitant malignancies of different origins in one organ especially with patients who had a history of malignancy in another organ.
一位有多个肺肿块且有肺外器官恶性肿瘤病史的患者，更有可能被诊断为转移性肺癌而非原发性肺癌。转移性癌症很少会与原发性癌症共存。我们遇到了一例同时诊断为原发性小细胞肺癌和子宫恶性混合性苗勒管肿瘤（MMMT）肺转移的病例。该患者是一名52岁女性，有股骨骨折和多个肺肿块，曾接受子宫MMMT手术。通过支气管镜活检诊断为小细胞肺癌。小细胞肺癌化疗后中央肺肿块缩小，但多个外周肿块增大。对其中一个外周肿块进行经皮活检显示为转移性子宫MMMT。我们建议，对于有其他器官恶性肿瘤病史的患者，尤其是在一个器官中，必须考虑可能存在不同起源的合并恶性肿瘤。
