恶性混合性中胚层肿瘤：生物学与临床方面

Malignant mixed mesodermal tumours: biology and clinical aspects.

作者信息

Gourley C, Al-Nafussi A, Abdulkader M, Smyth J F, Gabra H

机构信息

ICRF Medical Oncology Unit, MRC Building, Western General Hospital, EH4 2XU, Edinburgh, UK.

出版信息

Eur J Cancer. 2002 Jul;38(11):1437-46. doi: 10.1016/s0959-8049(02)00114-4.

DOI:10.1016/s0959-8049(02)00114-4

PMID:12110488

Abstract

Mixed mesodermal tumours (MMTs) are relatively rare gynaecological tumours that have been poorly studied in clinical and molecular terms. They are chemosensitive (at least initially), although ultimately they have a poor prognosis. The biology of the tumour is fascinating in view of its composition of both epithelial and mesenchymal entities. We review herein the literature on the clinical and biological aspects of this malignancy.

摘要

混合性中胚叶肿瘤（MMTs）是相对罕见的妇科肿瘤，在临床和分子层面上的研究较少。它们对化疗敏感（至少在初始阶段如此），尽管最终预后较差。鉴于其由上皮和间充质成分组成，该肿瘤的生物学特性令人着迷。我们在此回顾关于这种恶性肿瘤临床和生物学方面的文献。