Jung Chi Young, Kwon Kun Young
Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Tuberc Respir Dis (Seoul). 2012 Jul;73(1):61-6. doi: 10.4046/trd.2012.73.1.61. Epub 2012 Jul 31.
Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type (extranodal MZL) is a distinct subgroup of non-Hodgkin's lymphoma. Pulmonary extranodal MZL is a rare entity and accounts for less than 0.5% of primary pulmonary malignancies. Only a few cases of simultaneous occurrence of lung cancer and pulmonary extranodal MZL have been reported. A 60-year-old woman was referred to our hospital with a pulmonary nodule. She was diagnosed with lung adenocarcinoma by percutaneous needle biopsy. The protrusions into the left main bronchus were found by accident while performing bronchoscopy during lung cancer evaluation. The bronchial lesions were diagnosed as extranodal MZL. Although the patient underwent surgical resection for the lung adenocarcinoma, the pulmonary extranodal MZL was left untreated; it was monitored during follow-up visits. To our knowledge, this is the first report of synchronous lung adenocarcinoma and primary extranodal MZL of the main bronchus.
黏膜相关淋巴组织型结外边缘区B细胞淋巴瘤（结外MZL）是非霍奇金淋巴瘤的一个独特亚组。肺结外MZL是一种罕见的疾病，占原发性肺恶性肿瘤的比例不到0.5%。仅有少数肺癌与肺结外MZL同时发生的病例报道。一名60岁女性因肺部结节转诊至我院。经皮针吸活检诊断为肺腺癌。在肺癌评估期间进行支气管镜检查时意外发现左主支气管有突出物。支气管病变被诊断为结外MZL。尽管患者接受了肺腺癌的手术切除，但肺结外MZL未予治疗；在随访期间对其进行监测。据我们所知，这是首例同步发生的肺腺癌和主支气管原发性结外MZL的报道。
