Xie Ren Guo, Tang Jin Bo
Department of Hand Surgery, The Hand Surgery Research Center, Affiliated Hospital of Nantong University, 20 West Temple Road, Nantong, Jiangsu, China.
Hand Clin. 2012 Nov;28(4):503-9. doi: 10.1016/j.hcl.2012.08.011.
Tendons are made of compact dense collagen fibers with only sparse cellularity and naturally low immunogenicity. Allogenic tendons may be preserved through deep freezing methods and retain excellent mechanical properties after revitalization. Allogenic tendons were used in 22 patients (30 tendons) for second-stage tendon reconstruction in the hand. Preliminary results indicate no observable adverse tissue reactions, and functional recovery after tendon grafting does not seem different from reconstruction using tendon autografts. This type of allogenic graft does not seem to produce serious concern as a foreign tissue in the body, at least in the short term.
肌腱由紧密排列的致密胶原纤维构成,细胞成分稀少,天然免疫原性低。同种异体肌腱可通过深冻方法保存,复温后保留优异的力学性能。22例患者(30条肌腱)在手部二期肌腱重建中使用了同种异体肌腱。初步结果显示未观察到不良组织反应,肌腱移植后的功能恢复似乎与自体肌腱重建无异。至少在短期内,这种同种异体移植物作为体内的外来组织似乎并未引起严重担忧。