Hagiga Ahmed, Chiew Daphne Le Min, Radhi Mohamed A, Mistry Rikki, Dheansa Baljit
Queen Victoria Hospital NHS Foundation Trust, East Grinstead, UK.
Whittington Health NHS Trust, London, UK.
Plast Surg (Oakv). 2025 Feb;33(1):85-93. doi: 10.1177/22925503231190924. Epub 2023 Aug 10.
Tendon grafting is standard for treating tendon defects. Allografts are popular in cruciate ligament reconstruction but not yet in upper limb tendon reconstruction. A scoping review was conducted to map the existing practice of allograft use in hand surgery for tendon reconstruction and identify gaps in knowledge for future research. Two independent reviewers searched MEDLINE and SCOPUS databases for studies on upper limb tendon reconstruction using tendon allografts until June 2022. Eligible studies included controlled randomised clinical trials, cohort, case-control, cross-sectional, or case report and series studies conducted in English and enrolling patients who underwent tendon allograft reconstruction in the upper limb. Screening for eligibility was done by both reviewers, who reached a consensus through discussion, with no exclusion based on poor methodological quality. Data charting included study title, patients' demographics and outcomes, complications, and follow-up period. The database search found 6 eligible articles with a total of 116 patients and 148 allografts used for reconstruction. Of the studies that looked at functional outcomes, 72.9% of patients had 'good' or 'fair' results, while 25.8% were classed as 'poor'. All of the patients assessed for subjective outcomes were at least partially/fairly satisfied with the allograft. This scoping review has indicated that the utilisation of tendon allografts in the upper limb can potentially be a promising approach for tendon reconstruction, especially in cases of severe trauma or salvage. However, further research is needed to comprehensively assess efficacy, long-term outcomes, complications, postoperative rehabilitation protocols, and comparative effectiveness against autograft tendon reconstruction.
肌腱移植是治疗肌腱缺损的标准方法。同种异体移植物在交叉韧带重建中很常用,但在上肢肌腱重建中尚未广泛应用。本综述旨在梳理手部手术中使用同种异体移植物进行肌腱重建的现有实践,并找出未来研究的知识空白。两名独立评审员在MEDLINE和SCOPUS数据库中检索了截至2022年6月的关于使用同种异体肌腱进行上肢肌腱重建的研究。符合条件的研究包括对照随机临床试验、队列研究、病例对照研究、横断面研究,或用英文发表且纳入了接受上肢同种异体肌腱重建患者的病例报告及系列研究。两名评审员共同进行资格筛选,通过讨论达成共识,不基于方法学质量差而排除任何研究。数据记录包括研究标题、患者人口统计学特征和结局、并发症以及随访期。数据库检索发现6篇符合条件的文章,共涉及116例患者和148条用于重建的同种异体肌腱。在关注功能结局的研究中,72.9%的患者结果为“良好”或“尚可”,而25.8%被归类为“差”。所有接受主观结局评估的患者对同种异体移植物至少部分/还算满意。本综述表明,在上肢使用同种异体肌腱进行重建可能是一种有前景的方法,尤其是在严重创伤或挽救性手术的情况下。然而,需要进一步研究以全面评估其疗效、长期结局、并发症、术后康复方案以及与自体肌腱重建相比的相对有效性。