Department of Chemistry, University of Houston, Houston, Texas 77204-5003, USA.
J Am Chem Soc. 2012 Nov 7;134(44):18237-40. doi: 10.1021/ja3092278. Epub 2012 Oct 29.
An auxiliary-assisted, copper catalyzed or promoted sulfenylation of benzoic acid derivative β-C-H bonds and benzylamine derivative γ-C-H bonds has been developed. The method employs disulfide reagents, copper(II) acetate, and DMSO solvent at 90-130 °C. Application of this methodology to the direct trifluoromethylsulfenylation of C-H bonds was demonstrated.
开发了一种辅助的、铜催化或促进的苯甲酸衍生物β-C-H 键和苄胺衍生物γ-C-H 键的磺酰化反应。该方法采用二硫化物试剂、醋酸铜和 DMSO 溶剂,在 90-130°C 下进行。该方法学在 C-H 键的直接三氟甲磺酰化中的应用得到了证明。