Division of Infectious Diseases, Springfield Clinic, Springfield, IL 62701, USA.
Med Clin North Am. 2012 Nov;96(6):1193-202. doi: 10.1016/j.mcna.2012.08.003.
NSTI is a life-threatening, surgical, and medical emergency. Clinical presentation, at least in the initial phase, can be misleading. Various studies have shown that delay in surgical debridement is associated with increased mortality. A high index of suspicion is important in early recognition and in instituting prompt therapy without delay. Early diagnosis, aggressive surgical debridement, aggressive supportive care, and optimal presumptive antibiotic therapy significantly improve morbidity and mortality associated with NSTIs.
NSTI 是一种危及生命的外科和医学急症。临床表现，至少在初始阶段，可能具有误导性。多项研究表明，手术清创的延迟与死亡率的增加有关。早期识别和及时进行治疗而不延误，高度怀疑是很重要的。早期诊断、积极的手术清创、积极的支持治疗和最佳的经验性抗生素治疗显著改善了 NSTI 相关的发病率和死亡率。
