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冠状动脉搭桥术后的菌血症和胸骨感染

Bacteremia and sternal infection after coronary artery bypass grafting.

作者信息

Kohman L J, Coleman M J, Parker F B

机构信息

State University of New York Health Science Center, Syracuse.

出版信息

Ann Thorac Surg. 1990 Mar;49(3):454-7. doi: 10.1016/0003-4975(90)90254-4.

Abstract

Sternal wound infection remains a source of substantial morbidity and mortality after coronary artery bypass grafting. We noted an association between bacteremias and sternal wound complications in these patients. A review of 835 consecutive coronary bypass patients showed a 3.2% incidence of bacteremia and a 1.9% incidence of deep and superficial sternal wound infection. The sternal wound was the most common source of bacteremia, accounting for 59% of the infections. Coagulase-negative Staphylococcus was responsible for one half of the sternal wound infections. Often, a positive blood culture was the first manifestation of wound infection, occurring before local signs were manifest. We recommend multiple blood cultures in postoperative coronary bypass patients with pronounced fever. If no source of infection can be identified, sternal wound aspirate may be revealing. Appropriate early wound management can then be carried out, maximizing chances for good recovery.

摘要

在冠状动脉搭桥术后,胸骨伤口感染仍然是导致严重发病和死亡的一个原因。我们注意到这些患者的菌血症与胸骨伤口并发症之间存在关联。对835例连续的冠状动脉搭桥患者进行的回顾显示,菌血症的发生率为3.2%,深部和浅部胸骨伤口感染的发生率为1.9%。胸骨伤口是菌血症最常见的来源,占感染的59%。凝固酶阴性葡萄球菌导致了一半的胸骨伤口感染。通常,血培养阳性是伤口感染的首发表现,出现在局部体征出现之前。我们建议对术后有明显发热的冠状动脉搭桥患者进行多次血培养。如果找不到感染源,胸骨伤口抽吸物可能会有所提示。然后可以进行适当的早期伤口处理,以最大程度地提高良好恢复的机会。

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