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全膝关节置换术后长期疼痛和功能障碍,连续股神经阻滞加单次或连续坐骨神经阻滞与不加阻滞的比较:一项前瞻性、随机对照临床试验的 1 年随访。

Long-term pain and functional disability after total knee arthroplasty with and without single-injection or continuous sciatic nerve block in addition to continuous femoral nerve block: a prospective, 1-year follow-up of a randomized controlled trial.

机构信息

Department of Anesthesiology, Academic Medical Center, University of Amsterdam, The Netherlands.

出版信息

Reg Anesth Pain Med. 2013 Jan-Feb;38(1):58-63. doi: 10.1097/AAP.0b013e318272523c.

Abstract

BACKGROUND AND OBJECTIVES

This is a follow-up to determine long-term outcomes after total knee arthroplasty (TKA) in patients enrolled in a previous randomized trial that found reduced postoperative pain after addition of sciatic nerve block to continuous femoral nerve block for TKA.

METHODS

Physical function after TKA was evaluated at 3 and 12 months in patients (n = 89) receiving continuous femoral nerve block alone (group F), combined with a single-injection (group Fs) or continuous sciatic nerve block (group FCS) after TKA, until the second postoperative day. Physical function, stiffness, and pain were measured by using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Oxford Knee Score 12-item knee questionnaires, and visual analog scale at rest and during mobilization before TKA and 3 and 12 months afterward. Post hoc, a median split on poor functioning (WOMAC) was analyzed.

RESULTS

Western Ontario and McMaster Universities Osteoarthritis Index, Oxford Knee Score 12-item knee, and visual analog scale scores improved significantly in all patients, without any differences among groups. Median (range) WOMAC at 3 months were in group F, 83 (20-97); group Fs, 72 (25-99); and group, FCS 76 (28-100) and at 12 months 87 (35-98), 77 (43-100), and 89 (35-100), respectively.

CONCLUSIONS

No differences were detected in the secondary outcomes we examined. Thus, improved postoperative outcome did not translate into improved functional outcome or long-term pain.

摘要

背景与目的

本研究旨在对先前一项随机试验进行随访,以确定全膝关节置换术(TKA)后患者的长期结局。该试验发现,在 TKA 中连续股神经阻滞的基础上增加坐骨神经阻滞可减少术后疼痛。

方法

在 TKA 后,连续股神经阻滞组(F 组)、单次注射坐骨神经阻滞组(Fs 组)和连续坐骨神经阻滞组(FCS 组)患者(n=89)中,评估术后 3 个月和 12 个月的膝关节功能。物理功能、僵硬和疼痛采用 Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC)、Oxford Knee Score 12-item knee questionnaire 和视觉模拟评分(VAS)在 TKA 前、后 3 个月和 12 个月进行评估。术后对 WOMAC 评分差(<70)进行中位数分割分析。

结果

所有患者的 WOMAC、Oxford Knee Score 12-item knee 和 VAS 评分均显著改善,组间无差异。F 组 3 个月时 WOMAC 中位数(范围)为 83(20-97),Fs 组为 72(25-99),FCS 组为 76(28-100);12 个月时分别为 87(35-98)、77(43-100)和 89(35-100)。

结论

我们未检测到次要结局的差异。因此,术后结局的改善并未转化为功能结局或长期疼痛的改善。

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