From the *Department of Anesthesiology, Tokyo Women's Medical University, Tokyo; and †Department of Anesthesiology, Kitano Hospital, Osaka, Japan.
Reg Anesth Pain Med. 2014 May-Jun;39(3):225-9. doi: 10.1097/AAP.0000000000000076.
The benefit of adding sciatic nerve block (SNB) to femoral nerve block to improve analgesia after total knee arthroplasty (TKA) is uncertain. We hypothesized that the effective duration of single-injection SNB is too short to improve postoperative analgesia and that this contributes to conflicting results on the efficacy of SNB after TKA. We evaluated this hypothesis in a prospective double-blind randomized controlled trial.
Sixty patients undergoing TKA were randomly allocated to a continuous SNB group or a single-injection SNB group. All patients received femoral nerve block (0.5% ropivacaine 20 mL) and SNB (0.2% ropivacaine 20 mL) and catheters were inserted into both peripheral nerve block sites before surgery. Both groups received continuous femoral nerve block and patient-controlled intravenous analgesia with morphine. Continuous SNB (0.2% ropivacaine 5 mL/h; continuous SNB group) or sham continuous SNB (0.9% normal saline 5 mL/h; single-injection SNB group) was provided after surgery. The primary outcome was total morphine consumption for 48 hours after surgery.
Total morphine consumption in the 48-hour period after surgery was significantly lower in the continuous SNB group compared with the single-injection SNB group [4.9 (5.9) vs 9.7 (9.5) mg, P = 0.002]. Visual analog scale pain scores at rest were also significantly lower in the continuous SNB group (P = 0.035).
The combination of continuous femoral and SNB provides a superior opioid sparing effect and improves analgesia after TKA.
在全膝关节置换术后,添加坐骨神经阻滞(SNB)以改善镇痛效果的益处尚不确定。我们假设单次注射 SNB 的有效持续时间太短,无法改善术后镇痛效果,这也是导致 SNB 在 TKA 后疗效存在争议的原因。我们在一项前瞻性、双盲、随机对照试验中对此假设进行了评估。
60 例接受 TKA 的患者被随机分配至连续 SNB 组或单次注射 SNB 组。所有患者均接受股神经阻滞(0.5%罗哌卡因 20 mL)和 SNB(0.2%罗哌卡因 20 mL),并在手术前将导管插入外周神经阻滞部位。两组患者均接受连续股神经阻滞和吗啡患者自控静脉镇痛。术后,连续 SNB 组(0.2%罗哌卡因 5 mL/h;连续 SNB 组)或假连续 SNB 组(0.9%生理盐水 5 mL/h;单次注射 SNB 组)提供连续 SNB。主要结局为术后 48 小时内的总吗啡消耗量。
与单次注射 SNB 组相比,连续 SNB 组术后 48 小时内的总吗啡消耗量显著降低[4.9(5.9)mg 比 9.7(9.5)mg,P = 0.002]。连续 SNB 组静息时的视觉模拟评分疼痛也显著降低(P = 0.035)。
连续股神经和 SNB 的联合应用可提供更好的阿片类药物节省效果,并改善 TKA 后的镇痛效果。