子痫产妇死亡的危险因素：167 例子痫病例分析。

Risk factors for maternal mortality in eclampsia: analysis of 167 eclamptic cases.

机构信息

Department of Obstetrics and Gynecology, School of Medicine, Dicle University, Diyarbakir, Turkey.

出版信息

Eur Rev Med Pharmacol Sci. 2012 Oct;16(10):1399-403.

PMID:23104656

Abstract

BACKGROUND

The aim of this study was to evaluate risk factors associated with maternal mortality in patients with eclampsia.

METHODS

The probable risk factors of maternal mortality including maternal age, length of hospital stay, gestational age, systolic and diastolic blood pressures; hematocrit, hemoglobin, platelet count, levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase were determined from patients' charts and Odds ratios (OR) of these factors were detected using by logistic regression analysis.

RESULTS

According to logistic regression model, AST [OR, (95% Confidence Interval, CI): 7.39 (2.71-20.13)]; ALT [6.45 (2.42-17.16)]; postpartum diastolic blood pressure [4.58 (1.80-11.62)]; hematocrit [3.52 (1.86-6.65)]; hemoglobin [2.67 (2.01-3.55)] were found to be significant risk factors for maternal mortality.

CONCLUSIONS

In eclamptic patients, close monitoring of particular laboratory values and blood pressure, and early intervention to alterations of certain variables will provide possibility for prevention against potential complications and subsequently decreasing mortality.

摘要

背景

本研究旨在评估子痫患者发生孕产妇死亡的相关危险因素。

方法

从患者病历中确定可能导致孕产妇死亡的风险因素，包括产妇年龄、住院时间、胎龄、收缩压和舒张压；血细胞比容、血红蛋白、血小板计数、丙氨酸氨基转移酶（ALT）、天门冬氨酸氨基转移酶（AST）、乳酸脱氢酶水平，并使用 logistic 回归分析检测这些因素的优势比（OR）。

结果

根据 logistic 回归模型，AST [OR，（95%置信区间，CI）：7.39（2.71-20.13）]；ALT [6.45（2.42-17.16）]；产后舒张压 [4.58（1.80-11.62）]；血细胞比容 [3.52（1.86-6.65）]；血红蛋白 [2.67（2.01-3.55）] 是孕产妇死亡的显著危险因素。