Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.
Jpn J Ophthalmol. 2013 Jan;57(1):57-62. doi: 10.1007/s10384-012-0207-7. Epub 2012 Oct 27.
To observe long-term changes in intraocular pressure (IOP) after a combined phacoemulsification, intraocular lens implantation, and vitrectomy procedure.
This was a retrospective case series at a single hospital. Of 105 consecutive cases that received combined phacoemulsification, intraocular lens implantation, and vitrectomy for macular hole or epiretinal membrane, 85 eyes (patients) were followed up for 1 year or longer. The IOP of both eyes in the subjects who had surgery in one eye was measured at baseline and at 1, 3, 6, 12, 24, 36, 48, and 60 months postoperatively. The IOP of the treated eye was compared with the fellow eye and with the baseline value at each follow-up visit.
Intraocular pressure in the operated eyes at 3 months after surgery was significantly lower than that at baseline and than that in the respectively fellow eyes (P < 0.001, paired-t test with Bonferroni correction). The IOP subsequently returned to the baseline value or was the same as that of the fellow eye within 3 months of the observation time point. Only two treated eyes had elevated IOP exceeding 21 mmHg after 6 months postoperatively.
The change in the IOP after phacovitrectomy may be limited, and care when using this procedure because some eyes show increased IOP compared to the fellow eye after a long period.
观察白内障超声乳化吸除联合眼内人工晶状体植入及玻璃体切割术后眼内压（IOP）的长期变化。
这是一项单中心回顾性病例系列研究。对 105 例连续接受白内障超声乳化吸除联合眼内人工晶状体植入及玻璃体切割术治疗黄斑裂孔或视网膜前膜的患者中的 85 只眼（患者）进行了 1 年或更长时间的随访。对每只眼手术的受试者，在基线时以及术后 1、3、6、12、24、36、48 和 60 个月时测量双眼的 IOP。在每次随访时，比较治疗眼的 IOP 与对侧眼和基线值。
术后 3 个月时手术眼的 IOP 明显低于基线值和对侧眼（P < 0.001，配对 t 检验，Bonferroni 校正）。随后，IOP 在 3 个月的观察时间内恢复到基线值或与对侧眼相同。仅 2 只治疗眼在术后 6 个月后出现高于 21mmHg 的眼压升高。
白内障超声乳化联合玻璃体切割术后的 IOP 变化可能是有限的，因此在使用该手术时需要谨慎，因为一些眼在较长时间后与对侧眼相比会出现眼压升高。
