正常人和癌症患者使用绿玉树根凝集素后的红细胞凝集差异模式
Differential erythrocyte agglutination pattern in normal and cancer patients with Synadenium grantii root (Hook f) lectin.
作者信息
Durgawale P P, Shukla P S, Sontakke S D, Chougule P G
机构信息
Dept of Biochemistry, Krishna Institute of Medical Sciences, 415110 Karad.
出版信息
Indian J Clin Biochem. 2001 Jan;16(1):110-2. doi: 10.1007/BF02867578.
In the present study the property of lectin agglutination in blood on normal and different cancer patients has been observed. The purifiedSynadenium grantii root lectin was non blood group specific and its utility as a diagnostic tool in malignancy was studied. Hemagglutination (units/ml) of red blood cells of different types of cancer was compared with the normal control's red blood cells. Out of 113 total cancer patients, only a group of 29 breast cancer patients showed significant increase in titre value (P<0.05) compared to normal control.
在本研究中，观察了正常人和不同癌症患者血液中的凝集素凝集特性。对纯化的格氏腺叶豆根凝集素进行了研究，其不具有血型特异性，并探讨了其作为恶性肿瘤诊断工具的效用。将不同类型癌症患者红细胞的血凝（单位/毫升）与正常对照的红细胞进行了比较。在总共113例癌症患者中，只有一组29例乳腺癌患者的滴度值与正常对照相比有显著升高（P<0.05）。
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