心脏疾病和非心脏疾病中的心肌肌钙蛋白T及肌酸激酶同工酶（质量）水平
Cardiac troponin-T and CK-MB (mass) levels in cardiac and non cardiac disease.
作者信息
Reddy G Chinnapu, Kusumanjali G, Sharada A H R, Rao Pragna
机构信息
Kamineni Institute of Medical Sciences, Narketpally, 508 254 Nalgonda District, Andhra Pradesh.
出版信息
Indian J Clin Biochem. 2004 Jul;19(2):91-4. doi: 10.1007/BF02894263.
Abstract
Serum cardiac troponin T (cTnT) and CKMB (mass) were analysed in three groups of patients. The first group (n=32) were patients with acute coronary syndromes including myocardial infarction. The second group (n=35)were patients with hypertension. The third group (n=24) were patients who had succumbed to non cardiac diseases. In all 3 groups, cardiac troponin T was elevated when compared with controls (p<0.001). However, CKMB elevation was not significant in all groups. CKMB levels correlated well with troponin T levels only when CKMB was greater than 50 ng/ml (r=1.00). Small elevations of troponin T identifies minimal cardiac necrosis and patients can benefit from early invasive therapy.
摘要
对三组患者的血清心肌肌钙蛋白T（cTnT）和肌酸激酶同工酶（质量）进行了分析。第一组（n = 32）是患有急性冠状动脉综合征包括心肌梗死的患者。第二组（n = 35）是高血压患者。第三组（n = 24）是死于非心脏疾病的患者。在所有三组中，与对照组相比，心肌肌钙蛋白T升高（p<0.001）。然而，并非所有组的肌酸激酶同工酶都显著升高。只有当肌酸激酶同工酶大于50 ng/ml时，其水平才与肌钙蛋白T水平密切相关（r = 1.00）。肌钙蛋白T的小幅升高表明存在轻微的心肌坏死，患者可从早期侵入性治疗中获益。
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