Bhagwat V R, Subrahmanyam M, Pujari K N
Department of Biochemistry, SBH Government Medical College, Chakkarbardi, Malegaon Road, 424 001 Dhule.
Indian J Clin Biochem. 2007 Sep;22(2):154-7. doi: 10.1007/BF02913336.
Various metabolic and biological changes follow burn injury. Serum Thio-barbituric acid reactive substances (TBARS), transaminases, alkaline phosphatase and amylase were measured in 43 patients with thermal injury over the first 10 days of post burn period. No clear correlation between elevated serum enzymes except amylase and the burn size was observed on admission. Mean serum TBARS were significantly increased in the burn patients. Transaminases values increased till 5(th) day then declined on 10(th) day, whereas alkaline phosphatase and amylase activities continued to rise till day 10. It is concluded that functional disturbances occur in liver and pancreas around a week after thermal injury. Monitoring serum ALP and amylase in postburn period has valuable prognostic importance.
烧伤后会出现各种代谢和生物学变化。在43例热烧伤患者烧伤后的前10天内，检测了血清硫代巴比妥酸反应性物质（TBARS）、转氨酶、碱性磷酸酶和淀粉酶。入院时，除淀粉酶外，血清酶升高与烧伤面积之间未观察到明显相关性。烧伤患者的平均血清TBARS显著升高。转氨酶值在第5天升高，然后在第10天下降，而碱性磷酸酶和淀粉酶活性持续升高至第10天。结论是热烧伤后约一周肝脏和胰腺会出现功能障碍。烧伤后监测血清碱性磷酸酶和淀粉酶具有重要的预后意义。
