Houston A B, Pollock J C, Doig W B, Gnanapragasam J, Jamieson M P, Lilley S, Murtagh E P
Department of Cardiology, Royal Hospital for Sick Children, Glasgow.
Br Heart J. 1990 Jan;63(1):50-4. doi: 10.1136/hrt.63.1.50.
Four infants and children with anomalous connection of the left coronary artery to the pulmonary trunk were studied with colour Doppler flow mapping. In three the diagnosis was only suspected when the colour Doppler study showed dilated intraseptal and epicardial vessels and an abnormal flow signal into the pulmonary artery in diastole; this latter signal localised the exact site of communication, which was not apparent on angiocardiography. Two of these patients had previously had operations for severe mitral regurgitation, the diagnosis of anomalous left coronary artery having been previously considered in one but missed despite aortic root angiography. The colour study in the fourth was largely confirmatory, operation without catheterisation being undertaken on the basis of the echocardiographic images. By contrast in two infants subsequently seen with congestive cardiomyopathy the demonstration of flow direction in the left coronary artery confirmed that it was normally connected to the aorta. Colour Doppler flow mapping can show flow direction in the left coronary artery and from the mouth of an anomalous coronary artery into the pulmonary artery, thus simplifying the diagnosis and allowing the site of the connection of the left coronary artery to the pulmonary artery to be determined with precision.
对4例左冠状动脉异常连接至肺动脉干的婴幼儿进行了彩色多普勒血流显像研究。其中3例,仅在彩色多普勒检查显示室间隔内和心外膜血管扩张以及舒张期肺动脉内出现异常血流信号时才怀疑有此诊断;后一信号确定了交通的确切部位,而这在心血管造影时并不明显。这2例患者先前因严重二尖瓣反流接受过手术,其中1例曾考虑过左冠状动脉异常的诊断,但尽管进行了主动脉根部造影仍被漏诊。第4例的彩色检查在很大程度上起到了确诊作用,根据超声心动图图像未进行心导管检查即实施了手术。相比之下,随后见到的2例充血性心肌病婴幼儿,左冠状动脉内血流方向的显示证实其正常连接至主动脉。彩色多普勒血流显像可显示左冠状动脉内的血流方向以及异常冠状动脉口至肺动脉的血流方向,从而简化诊断并能精确确定左冠状动脉与肺动脉的连接部位。