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[手部先天性畸形的动脉模式(作者译)]

[Arterial patterns in congenital deformities of the hand (author's transl)].

作者信息

Sudo Y

出版信息

Nihon Seikeigeka Gakkai Zasshi. 1979 Nov;53(11):1627-40.

PMID:231074
Abstract

Etiology of congenital deformities of the hand is still unknown in most cases. But anomalous development of arteries has been suspected to play a role in faulty development of the hands. Senior (1926) and Singer (1933) have reported arterial anomalies in the developmental stage of these vessels. Between 1968 and 1978, 367 patients with 453 congenital deformities of the hand visited the hand service of Kyoto University Hospital. These hand anomalies were classified according to Swanson's classification. Angiography was performed on 74 hands of 70 patients in this series, and attempts were made to correlate these with the types of the deformities. From the standpoint of embryological development of arteries, it is concluded that failure of formation of parts (arrest of development), failure of differentiation (separation) of parts and duplication are generated in the same stage from 48 days postovulatory (18 mm embryo), overgrowth (gigantism) of the hand and congenital constriction band syndrome are generated after 52 days postovulatory (23 mm embryo). Generalized skeletal anomalies are considered to be generated in the various developmental stages depending on the each malformed hands. Developmental stage of malformed hands with generalized skeletal abnormalities is discussed with special reference to the embryological development of other anomalies.

摘要

在大多数情况下,手部先天性畸形的病因仍不明确。但动脉的异常发育被怀疑在手部发育异常中起作用。西尼尔(1926年)和辛格(1933年)报告了这些血管发育阶段的动脉异常情况。1968年至1978年间,367例患有453处手部先天性畸形的患者前往京都大学医院手部诊疗科室就诊。这些手部畸形根据斯旺森分类法进行分类。对该系列中70例患者的74只手进行了血管造影,并试图将其与畸形类型相关联。从动脉胚胎发育的角度来看,得出的结论是,部分形成失败(发育停滞)、部分分化失败(分离)和重复在排卵后48天(18毫米胚胎)的同一阶段产生,手部过度生长(巨大症)和先天性束带综合征在排卵后52天(23毫米胚胎)后产生。全身性骨骼异常被认为是根据每只畸形手在不同发育阶段产生的。结合其他异常的胚胎发育情况,特别讨论了伴有全身性骨骼异常的畸形手的发育阶段。

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