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急性磷化铝(毒鼠磷)中毒后严重低血糖症;一例病例报告及文献复习

Severe hypoglycemia following acute aluminum phosphide (rice tablet) poisoning; a case report and review of the literature.

作者信息

Mehrpour Omid, Aghabiklooei Abbas, Abdollahi Mohammad, Singh Surjit

机构信息

Department of Clinical Toxicology and Forensic Medicine, Birjand University of Medical Sciences, Birjand, Iran.

出版信息

Acta Med Iran. 2012;50(8):568-71.

Abstract

Aluminum phosphide (AlP) as 3 g tablet is widely used in Iran to protect stored food grains from pests. Hyperglycemia following its ingestion has been already reported in the recent years but severe hypoglycemia is uncommon. Here, we report a 19 year old male who attempted suicide with one tablet of AlP and demonstrated severe hypoglycemia. Despite restoration of blood glucose concentration to normal, he failed to respond to supportive treatment and died. The possible mechanisms leading to severe hypoglycemia are discussed. Though severe hypoglycemia is rare following AlP poisoning, physicians managing such patients should be aware of it.

摘要

磷化铝(AlP)片剂(每片含3克)在伊朗被广泛用于保护储存的粮食免受虫害。近年来已有摄入磷化铝后发生高血糖的报道,但严重低血糖并不常见。在此,我们报告一名19岁男性,他吞服一片磷化铝企图自杀,并出现严重低血糖。尽管血糖浓度恢复正常,但他对支持治疗无反应并死亡。本文讨论了导致严重低血糖的可能机制。虽然磷化铝中毒后严重低血糖罕见,但治疗此类患者的医生应予以关注。

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