Maira G, Anile C, De Marinis L, Barbarino A
Institute of Neurosurgery, Catholic University, Rome, Italy.
Can J Neurol Sci. 1990 Feb;17(1):67-70. doi: 10.1017/s0317167100030067.
The long-term follow-up of the transsphenoidal microsurgical treatment in 119 consecutively operated women with a PRL-secreting adenoma is presented. An apparent total removal of the tumor was achieved in 98 cases with an enclosed tumor (58 grade 1 and 40 grade II). In the remaining cases the removal was considered partial. The achievement of persistent normal PRL basal levels was verified in 61 patients (44 grade I and 17 grade II) who had an apparent total removal of the adenoma. In the 37 remaining patients who were thought at surgery to have had total removal we have distinguished two groups: 30 patients showed a "relapse" or "persistence" of PRL levels below 200 ng/ml without clinical and radiological signs of tumor regrowth, and 7 patients with a PRL level higher than 200 ng/ml who had evidence of PRL-secreting tumor recurrence.
本文介绍了对119例连续接受经蝶窦显微手术治疗的分泌催乳素腺瘤女性患者的长期随访情况。98例肿瘤包膜完整的患者（58例为1级，40例为2级）实现了肿瘤的明显全切除。其余病例的切除被认为是部分切除。61例腺瘤明显全切除的患者（44例为1级，17例为2级）证实实现了催乳素基础水平持续正常。在手术时被认为已全切除的其余37例患者中，我们区分出两组：30例患者催乳素水平“复发”或“持续”低于200 ng/ml，无肿瘤复发的临床和影像学迹象；7例患者催乳素水平高于200 ng/ml，有分泌催乳素肿瘤复发的证据。
