Chambers D C
J Natl Med Assoc. 1979 Nov;71(11):1071-3.
The granular cell myoblastoma (granular cell tumor) is a rare lesion of mesodermal origin that occurs in many areas of the body, including the vulva in seven percent of cases. The exact origin of this tumor is still being investigated. However, nerve cell origin is generally accepted. Lesions of the vulva occur in any age group and must be biopsied to rule out carcinoma, hidradenomas, sebaceous cysts, and papillomas. The recurrence rate of incompletely excised lesions is 25 percent. The microscopic picture of the lesion may simulate carcinoma as a result of reactive hyperplasia of the overlying epidermis. Discovery of a mass on the vulva in any patient which on biopsy reveals a granular cell myoblastoma should lead the examiner to excise the lesion completely and also to search for other lesions at various sites of the body.
颗粒细胞瘤（粒细胞瘤）是一种罕见的中胚层起源病变，可发生于身体的许多部位，其中7%的病例发生于外阴。该肿瘤的确切起源仍在研究中。然而，神经细胞起源已被普遍接受。外阴病变可见于任何年龄组，必须进行活检以排除癌、汗腺腺瘤、皮脂腺囊肿和乳头状瘤。切除不完全的病变复发率为25%。由于上皮过度增生，病变的显微镜图像可能类似癌。任何患者在外阴发现肿块，活检显示为颗粒细胞瘤时，检查者应彻底切除病变，并在身体各个部位寻找其他病变。
