印度首例米氮平致 Stevens-Johnson 综合征。
First case of mirtazepine-induced Stevens-Johnson syndrome from India.
机构信息
Department of Medicine, Lady Hardinge Medical College, New Delhi, India.
出版信息
Indian J Pharmacol. 2012 Sep-Oct;44(5):656-8. doi: 10.4103/0253-7613.100411.
Abstract
A 28-year-old woman, a known case of systemic lupus erythematosus (SLE), was admitted with mucocutaneous ulceroerosive lesions with blisters and thrombocytopenia after taking antidepressant mirtazepine. Exacerbation of SLE and drug-induced eruption was diagnosed. Clinical and laboratory markers were suggestive of Stevens-Johnson syndrome. This is a rare adverse effect of the newer generation antidepressant mirtazepine.
摘要
一位 28 岁女性，已知患有系统性红斑狼疮（SLE），在服用抗抑郁药米氮平后出现黏膜皮肤溃疡性病变、水疱和血小板减少症而入院。诊断为 SLE 加重和药物引起的皮疹。临床和实验室标志物提示史蒂文斯-约翰逊综合征。这是新一代抗抑郁药米氮平的罕见不良反应。
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