Wengler U, Siegfried W
Pathologisch-anatomisches Institut der Universität Erlangen-Nürnberg.
Dtsch Med Wochenschr. 1990 Mar 16;115(11):418-21. doi: 10.1055/s-2008-1065024.
One day before his death, a 66-year-old man who had been suffering since childhood from a severely itching and repeatedly bleeding skin lesion was examined for the first time by a general practitioner who immediately advised hospitalization. On admission, an extensive rodent ulcer on his back was noted and septic shock diagnosed. Because of the hopeless diagnosis no life-supporting measures were undertaken. Postmortem examination revealed an 18 x 26 cm sized ulcerating basal cell carcinoma on the back with infiltration of the thoracic vertebrae and a fist-sized paravertebral abscess between the left upper and lower lobe of the lung and abscessing pneumonia. Two metastases each were found in the right lung and in both kidneys with the histologically characteristic picture of basal cell carcinoma. This case confirms the observation that this type of carcinoma has the potential for metastasizing, but it usually does not do so because of its biological characteristics and early curative excision.
在一名66岁男性去世前一天，一名全科医生首次对其进行了检查。该男子自幼患有严重瘙痒且反复出血的皮肤病变。全科医生立即建议其住院治疗。入院时，发现他背部有一个大面积的侵蚀性溃疡，并诊断为感染性休克。由于诊断结果不容乐观，未采取任何维持生命的措施。尸检显示，背部有一个大小为18×26厘米的溃疡性基底细胞癌，侵犯胸椎，在肺左上叶和下叶之间有一个拳头大小的椎旁脓肿以及脓肿性肺炎。在右肺和双肾中各发现两个转移灶，具有基底细胞癌的组织学特征性表现。该病例证实了这样的观察结果：这种类型的癌症有转移的可能性，但由于其生物学特性和早期根治性切除，通常不会发生转移。
