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有机磷杀虫剂敌百虫对鲤鱼(Cyprinus carpio)免疫反应的体内效应。I. 污染对抗体产生的影响与器官中残留水平的关系。

In vivo effect of the organophosphorus insecticide trichlorphon on the immune response of carp (Cyprinus carpio). I. Effect of contamination on antibody production in relation to residue level in organs.

作者信息

Cossarini-Dunier M, Demael A, Siwicki A K

机构信息

Laboratoire d'Ecotoxicologie, INRA, Ecole Nationale Vétérinaire de Lyon, Marcy L'Etoile, France.

出版信息

Ecotoxicol Environ Saf. 1990 Feb;19(1):93-8. doi: 10.1016/0147-6513(90)90083-h.

Abstract

The organophosphorus insecticide trichlorphon was tested at medium (10 and 20 ppm) and high concentrations (20,000 ppm) on antibody production against Yersinia ruckeri vaccine. No statistically significant effect was observed on humoral response or on hematocrit. Contamination of organs was analyzed by acetylcholinesterase activity. At 20,000 ppm only liver and brain were highly contaminated; spleen and lymphocytes were not significantly contaminated. At 20 ppm no residue was found in organs.

摘要

使用有机磷杀虫剂敌百虫的中等浓度(10和20 ppm)和高浓度(20,000 ppm)测试其对鲁氏耶尔森氏菌疫苗抗体产生的影响。未观察到对体液反应或血细胞比容有统计学上的显著影响。通过乙酰胆碱酯酶活性分析器官的污染情况。在20,000 ppm浓度下,仅肝脏和大脑受到高度污染;脾脏和淋巴细胞未受到显著污染。在20 ppm浓度下,未在器官中发现残留。

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