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瓦武阿(科特迪瓦)人体锥虫病疫区。临床、寄生虫学及血清免疫学调查(作者译)

[Human trypanosomiasis focus of Vavoua (Ivory Coast). A clinical, parasitological and sero-immunological survey (author's transl)].

作者信息

Duvallet G, Stanghellini A, Saccharin C, Vivant J F

出版信息

Med Trop (Mars). 1979 Sep-Oct;39(5):517-26.

PMID:231175
Abstract

Vavoua human trypanosomiasis focus, located 60 km north of Daloa (Ivory Coast Republic) is facing a period of hyperactivity. A medical survey has been conducted in 9 villages of this focus: 7.424 persons have been examined and 128 new cases diagnosed in the field after clinical and parasitological examinations. Indirect Fluorescence Antibody Test applied to dried blood blots, in the laboratory, revealed 266 immunological suspects to be reexamined. 185 suspects were reexamined, 104 of whom were diagnosed after tyrpanosomes had been found in blood or/and in gland juice. The microhaematocrit centrifuge technique gave good results. Most of the 232 new cases were in the classical first period (unaltered CSF). Authors are insisting on the importance of survey prospections allowing an early diagnosis of sleeping sickness and on the interest of an immunodiagnostic test in addition to classical techniques to diagnose asymptomatical forms.

摘要

位于达洛亚(科特迪瓦共和国)以北60公里处的瓦武阿人体锥虫病疫源地正处于活动频繁期。已对该疫源地的9个村庄进行了医学调查:共检查了7424人,经临床和寄生虫学检查后在实地诊断出128例新病例。在实验室对干血斑进行的间接荧光抗体试验显示,有266名免疫疑似者需重新检查。对185名疑似者进行了重新检查,其中104人在血液或/和腺体分泌物中发现锥虫后被确诊。微量血细胞比容离心技术取得了良好效果。232例新病例中的大多数处于典型的第一阶段(脑脊液未改变)。作者强调了进行调查性普查以早期诊断昏睡病的重要性,以及除传统技术外采用免疫诊断试验来诊断无症状病例的意义。

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