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乳腺中MFH样病变：一种高级别恶性叶状肿瘤。

MFH Mimic in Breast: A High-Grade Malignant Phyllodes Tumor.

作者信息

Hemalatha A L, Sindhuram V Sumana, Asha U

机构信息

Department of Pathology, Mysore Medical College & Research Institute, Irwin Road, Mysore 570001, India.

出版信息

Case Rep Pathol. 2012;2012:835687. doi: 10.1155/2012/835687. Epub 2012 Oct 17.

DOI:10.1155/2012/835687
PMID:23119211
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3483664/
Abstract

Malignant phyllodes tumor is usually diagnosed by the presence of benign duct-like epithelium and malignant mesenchymal tissue. In addition to the usual fibrosarcomatous features, the mesenchymal component may show areas resembling osteogenic sarcoma, chondrosarcoma, liposarcoma, leiomyosarcoma, rhabdomyosarcoma, malignant mesenchymoma, and, very rarely, malignant fibrous histiocytoma. We present one such rare case of malignant phyllodes tumor with malignant fibrous histiocytoma-like stromal differentiation.

摘要

恶性叶状肿瘤通常通过良性导管样上皮和恶性间充质组织的存在来诊断。除了常见的纤维肉瘤特征外，间充质成分可能显示出类似骨肉瘤、软骨肉瘤、脂肪肉瘤、平滑肌肉瘤、横纹肌肉瘤、恶性间叶瘤的区域，并且非常罕见地显示出恶性纤维组织细胞瘤的区域。我们报告了1例这样罕见的具有恶性纤维组织细胞瘤样间质分化的恶性叶状肿瘤病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5b6/3483664/d4d6ca043335/CRIM.PATHOLOGY2012-835687.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5b6/3483664/94d9b962ec82/CRIM.PATHOLOGY2012-835687.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5b6/3483664/ff411a5dde9d/CRIM.PATHOLOGY2012-835687.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5b6/3483664/8df952968dc6/CRIM.PATHOLOGY2012-835687.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5b6/3483664/d4d6ca043335/CRIM.PATHOLOGY2012-835687.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5b6/3483664/94d9b962ec82/CRIM.PATHOLOGY2012-835687.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5b6/3483664/ff411a5dde9d/CRIM.PATHOLOGY2012-835687.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5b6/3483664/8df952968dc6/CRIM.PATHOLOGY2012-835687.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5b6/3483664/d4d6ca043335/CRIM.PATHOLOGY2012-835687.004.jpg

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本文引用的文献

1
Phyllodes tumor with osteosarcomatous differentiation: a comparative immunohistochemical study between epithelial and mesenchymal cells.伴有骨肉瘤分化的叶状肿瘤：上皮细胞与间充质细胞的免疫组织化学对比研究
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恶性叶状肿瘤表现出间充质干细胞特征，乙醛脱氢酶/二唾液酸神经节苷脂可鉴定其肿瘤干细胞。
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