萎缩性鼻炎的组织病理学变化研究
Study of histopathological changes in atrophic rhinitis.
作者信息
Singh I, Raizada R M, Chautervedi V N, Jain S K, Ingole S N
机构信息
Departments of Otolaryngology and Pathology, Mahatma Gandhi Institute of Medical Science, Sevagram Maharastra, India.
出版信息
Indian J Otolaryngol Head Neck Surg. 1999 Jan;51(1):21-4. doi: 10.1007/BF02996838.
A punch biopsy from the inferior turbinate was taken in 71 consecutive cases of atrophic rhinitis and studied for histopahtological changes. Squamous metaplasia was seen in 85 percent of cases. Tunica propria showed granulation tissue (41 percent) and chronic inflammatory cellular infiltrate (32 percent). Mucosal glands were decreased in 42 percent of cases and absent in 28 percent. Areas of dilated vessels were observed in 35 percent and decreased vascularity in 59 percent of cases. These observations are similar to those reported by others. Total squamous metaplasia with keratinisation and hypertrophy was seen by us in one case. This has not been reported earlier.
对71例连续性萎缩性鼻炎患者的下鼻甲进行了打孔活检，并对其组织病理学变化进行了研究。85%的病例可见鳞状化生。固有层可见肉芽组织（41%）和慢性炎性细胞浸润（32%）。42%的病例黏膜腺减少，28%的病例黏膜腺缺如。35%的病例观察到血管扩张区域，59%的病例血管减少。这些观察结果与其他人报道的相似。我们在1例病例中观察到完全角化和肥大的鳞状化生。此前尚未有过此类报道。
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