阿拉哈巴德头颈癌的谱系
Spectrum of Head-Neck cancers at Allahabad.
作者信息
Ahluwalia H, Gupta S C, Singh M, Gupta S C, Mishra V, Singh P A, Walia D K
机构信息
S. P. M. & Biostatistician, M. L. N. Medical College & Associated S. R. N. Hospital, Allahabad, (U.P.).
出版信息
Indian J Otolaryngol Head Neck Surg. 2001 Jan;53(1):16-21. doi: 10.1007/BF02910972.
A retrospective study of Head-Neck malignancy was conducted at Allahabad over a period of twenty two years from 1975 to 1996. During this period, 5,386 new Head-Neck Cancer cases were reported. Peak presentation of males was in sixth decade and in females it was in fifth decade of life. The sex ratio in this series was 3∶6∶1 while reverse sex ratio was observed in malignancies of thyroid, alveolus-gingiva, nasal cavity and post-cricoid region. Oral cavity lesion was the predominant cancer followed by larynx and oropharyngeal malignancy. Histologically, majority (89.97%) were squamous cell carcinoma with varied differentiation. Factors responsible for the high incidence of Head-Neck Cancers are discussed. An argent need is felt for the prevention and cessation strategies to achieve the goal of smoke free society by the year 2000 as expressed by Dr. Knoop so as to revert back the present trend of preventable Head-Neck Cancers.
1975年至1996年的22年间，在阿拉哈巴德开展了一项关于头颈恶性肿瘤的回顾性研究。在此期间，共报告了5386例新发头颈癌病例。男性发病高峰在60岁，女性发病高峰在50岁。该系列研究中的男女比例为3∶6∶1，而在甲状腺、牙槽-牙龈、鼻腔和环状软骨后区的恶性肿瘤中观察到相反的性别比例。口腔病变是最主要的癌症，其次是喉癌和口咽恶性肿瘤。组织学上，大多数（89.97%）为不同分化程度的鳞状细胞癌。文中讨论了导致头颈癌高发的因素。正如克诺普博士所表达的，迫切需要采取预防和戒烟策略，以在2000年实现无烟社会的目标，从而扭转目前可预防的头颈癌的发展趋势。
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