Malik Vikas, Shukla G K, Bhatia Naresh
Department of Otorhinolaryngology, KGMC, Lucknow, India.
Indian J Otolaryngol Head Neck Surg. 2002 Oct;54(4):285-90. doi: 10.1007/BF02993744.
The present study was carried on forty-five patients of confirmed hypothyroidism. Complete clinical examination and laboratory investigations were done regarding audiological and vestibular system. It was found that hypothyroidism affects the ear at multiple sites producing various types of hearing impairment viz. conductive, sensorineural and mixed. Vestibular system was found to be affected only minimally. The patients were then given levothyroxine and follow-up was done when they were euthyroid, which revealed statistically significant improvement in hearing threshold in 30% ears, in which conductive impairment was more common to be improved. The middle ear compliance and pressure, on impedance audiometry, also improved significantly in 50% and 87.50% ears respectively. Statistically significant change was also observed in acoustic reflex threshold. Improvement was also noted in wave I, V and interpeak (I-V) latencies, on Brain stem Evoked Response Audiometry (statistically not significant). The results of auditory investigations suggest a causal relationship between hypothyroidism and hearing loss. The site of.
本研究针对45例确诊为甲状腺功能减退症的患者进行。对听觉和前庭系统进行了全面的临床检查和实验室检查。结果发现,甲状腺功能减退症会在多个部位影响耳朵,导致各种类型的听力障碍,即传导性、感音神经性和混合性。前庭系统仅受到轻微影响。随后给患者服用左甲状腺素,当他们的甲状腺功能恢复正常时进行随访,结果显示30%的耳朵听力阈值有统计学意义的改善,其中传导性损伤更常见于得到改善。在声阻抗测听中,中耳顺应性和压力分别在50%和87.50%的耳朵中也有显著改善。声反射阈值也观察到有统计学意义的变化。在脑干听觉诱发电位中,I波、V波和峰间(I-V)潜伏期也有改善(统计学上无显著意义)。听觉检查结果表明甲状腺功能减退症与听力损失之间存在因果关系。……的部位。