Trivedi Bhargavi, Ojha Tarun, Soni Nikhil Kumar, Bansal Monika, Sharma Kanika, Chhabra Biban
Department of ENT, Mahatma Gandhimedical College and Hospital, Jaipur, India.
Indian J Otolaryngol Head Neck Surg. 2023 Apr;75(Suppl 1):574-577. doi: 10.1007/s12070-023-03655-y. Epub 2023 Mar 15.
Thyroid hormone disorders are both congenital as well as acquired. According to a projection from several studies on thyroid diseases, it has been estimated that about 42 million people in India suffer from various kind of thyroid diseases (1) Thyroid hormone is closely associated with the development of the cognitive functions, thus deficiency of this hormone is said to have effect an overall impact on proper functioning of the body. The normal functioning of the thyroid gland and adequate levels in the blood are Needed for the formation and functioning of the middle ear, inner ear and the central auditory pathway. Thus, congenital hypothyroidism (CH) can be a potential risk factor for hearing impairment (2) if the hormones decrease or are absent during the development of the peripheral and central auditory system structures. This study was undertaken with the objective of studying the pattern of hearing loss in patients who have a deranged thyroid profile. The study was conducted among 50 patients who were known cases of thyroid disorder in the Otorhinolaryngology Department of our institute. The study was hospital based observational clinical study. The patients were subjected to thyroid profile test After this, those who satisfied the inclusion and exclusion criteria and were included, after detailed history and examination, patients were subjected to PTA, hearing loss was classified according to WHO guidelines. The age group of the patients was from 30-55 yrs. with the mean age being 42. On the basis of the t3, t4 and tsh levels, in the current study out of 50 patients,40 were hypothyroid (80%),with male to female ratio of 6:4. On pure tone audiometry, 15 patients had decreased hearing. The other 25 had normal hearing. The incidence of hearing loss in hypothyoroid patients in our study is 37.5%. On analaysis the PTA reports of these patients,9 patients (22.5%) had conductive hearing loss of mild variety, the mean value of hearing loss being 26.2 decibels. 2 (5%) patients had mixed variety of hearing loss, with sensorineural hearing loss at higher frequencies. All the remaining patients had sensorineural type of hearing loss, i.e., 10%. Of the 10 patients, that have hyperthyroidism 8 were female and 2 were male. 3 patients (30%) had hearing loss, all these 3 patients reported hearing losses at high frequencies and had moderate type of sensorineural hearing loss. Conclusion- From our current study, we could see that hearing loss is present in both extremes of thyroid hormone imbalance The dominant variety of hearing loss in thyroid disorder is sensorineural type, because thyroid hormone imbalance affects the inner ear function.
甲状腺激素紊乱既有先天性的,也有后天获得性的。根据几项关于甲状腺疾病的研究预测,据估计印度约有4200万人患有各种甲状腺疾病。(1)甲状腺激素与认知功能的发育密切相关,因此这种激素的缺乏据说会对身体的正常功能产生全面影响。甲状腺的正常功能以及血液中的适当水平是中耳、内耳和中枢听觉通路形成和发挥功能所必需的。因此,如果在外周和中枢听觉系统结构发育过程中激素减少或缺乏,先天性甲状腺功能减退症(CH)可能是听力障碍的一个潜在危险因素。(2)本研究的目的是研究甲状腺功能紊乱患者的听力损失模式。该研究在我院耳鼻喉科的50例已知甲状腺疾病患者中进行。该研究是一项基于医院的观察性临床研究。患者接受甲状腺功能检查。在此之后,那些符合纳入和排除标准并被纳入的患者,经过详细的病史和检查后,接受纯音听力测试(PTA),听力损失根据世界卫生组织指南进行分类。患者的年龄组为30 - 55岁,平均年龄为42岁。根据当前研究中50例患者的三碘甲状腺原氨酸(T3)、甲状腺素(T4)和促甲状腺激素(TSH)水平显示,40例为甲状腺功能减退(80%),男女比例为6:4。在纯音听力测试中,15例患者听力下降。另外25例听力正常。我们研究中甲状腺功能减退患者的听力损失发生率为37.5%。分析这些患者的PTA报告,9例(22.5%)患有轻度传导性听力损失,听力损失的平均值为26.2分贝。2例(5%)患者患有混合性听力损失,高频区有感音神经性听力损失。其余所有患者均有感音神经性听力损失,即10%。在10例甲状腺功能亢进患者中,8例为女性,2例为男性。3例(30%)有听力损失,所有这3例患者均报告高频区听力损失,患有中度感音神经性听力损失。结论——从我们目前的研究可以看出,甲状腺激素失衡的两个极端情况均存在听力损失。甲状腺疾病中占主导的听力损失类型是感音神经性的,因为甲状腺激素失衡会影响内耳功能。