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[红细胞腺苷酸激酶系统在亲子鉴定中的应用]

[The use of the erythrocyte adenylate kinase system in paternity suits].

作者信息

Szabó L, Soós M, Somogyi E

出版信息

Morphol Igazsagugyi Orv Sz. 1979 Oct;19(4):287-96.

PMID:231203
Abstract

Authors describe genetically determined polymorphisms, genetical feature and pattern of inheritance of the system of AK. Results and methods used in their studies first in the Hungarian population are reported. On the basis of examination of 1734 persons the incidence of the AK phenotypes was found as follows: AK 1 = 93,59%, AK 2 = 0,05%, and AK 2-1 6,34%. Values of gene frequency: AK1-0,9676, AK2-0,0322. According to the authors findings the maximal (theoretical) chance of the exclusion of paternity on the basis of AK system was 3,02%. In 844 cases of discussed paternity beside the investigation of the systems of A1A2BO, MN, Hp, Rh, Gm/a, x, b), InV(1), Gc, Ss, Kk, Fy(ab), VSP, PGM1, GPT and ADA the system of AK was also studied. In 191 cases (22,62%) the paternity could have been excluded. In 8 cases (0,94%) exclusion of the paternity have been based on the findings of the examination of AK system. In cases of discussed paternity authors recommend the examination of the AK system.

摘要

作者描述了AK系统的基因决定的多态性、遗传特征和遗传模式。报告了他们在匈牙利人群中首次进行研究时所使用的结果和方法。在对1734人进行检查的基础上,发现AK表型的发生率如下:AK 1 = 93.59%,AK 2 = 0.05%,AK 2-1 = 6.34%。基因频率值:AK1 = 0.9676,AK2 = 0.0322。根据作者的研究结果,基于AK系统排除父权的最大(理论)几率为3.02%。在844例讨论的父权案例中,除了对A1A2BO、MN、Hp、Rh、Gm/a、x、b)、InV(1)、Gc、Ss、Kk、Fy(ab)、VSP、PGM1、GPT和ADA系统进行调查外,还研究了AK系统。在191例(22.62%)案例中可能排除了父权。在8例(0.94%)案例中,基于AK系统的检查结果排除了父权。对于讨论的父权案例,作者建议检查AK系统。

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[The use of the erythrocyte adenylate kinase system in paternity suits].[红细胞腺苷酸激酶系统在亲子鉴定中的应用]
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