Sasindran Vivek, Ravikumar A
Dept of ENT, Head and Neck Surgery, Sri Ramachandra Medical College and Research Institute (DU), Porur, Chennai, 600 116 India.
Indian J Otolaryngol Head Neck Surg. 2008 Mar;60(1):62-5. doi: 10.1007/s12070-008-0020-2. Epub 2008 Apr 3.
A 8-year-old male presented with visual loss, diplopia, ptosis, pain behind the left eye, facial numbness and vomiting of one week duration. The ophthalmological, neurological and radiological examination showed a lesion of the left orbital apex with extension into the cavernous sinus. Examination of the nose and paranasal sinuses did not reveal any abnormality. Transnasal Endoscopic orbital decompression was performed and inflamed granulation tissue found in the orbital apex was removed. Microbiology showed fungal elements which on culture grew Aspergillosis flavus. Antifungal therapy with new generation oral drug (voriconazole) resulted in complete resolution of symptoms. Relevant literature is reviewed and discussed.
一名8岁男性出现视力丧失、复视、上睑下垂、左眼后疼痛、面部麻木及持续一周的呕吐症状。眼科、神经科及影像学检查显示左侧眶尖有病变并延伸至海绵窦。鼻及鼻窦检查未发现任何异常。进行了经鼻内镜眼眶减压术,切除了在眶尖发现的炎性肉芽组织。微生物学检查显示有真菌成分,培养后为黄曲霉菌。使用新一代口服药物(伏立康唑)进行抗真菌治疗后症状完全缓解。对相关文献进行了综述和讨论。