Soufi Mehdi, Bouziane Mohammed, Massrouri Rahal, Chad Bouziane
Division of Digestive Surgery, Oujda CHU, University Mohammed First, Oujda, Morocco.
Int J Surg Case Rep. 2013;4(1):68-71. doi: 10.1016/j.ijscr.2012.09.007. Epub 2012 Sep 28.
Gastrointestinal stromal tumours (GISTs) are uncommon intra-abdominal tumours. These tumours tend to arise with a higher frequency in the stomach and the small bowel. In fewer than 5% of cases, they originate primarily from extra-gastrointestinal tumours (EGISTs). Gastrointestinal stromal tumour of the pancreas is very rare. Only few cases have been published. We report the first case of stromal tumour of the pancreas with concomitant pancreas divisum.
A 39-year-old male who presented with constipation and abdominal pain. A computerized tomography demonstrated a 9cm pancreatic mass, without liver lesions. A Whipple procedure with segmental colectomy was performed with success. After 24months follow up, the patient is doing well and disease-free.
Mesenchymal tumours of the pancreas are extremely rare, accounting for less than 1% of all pancreatic tumours. The endoscopic ultrasound is helpful for diagnosis. Surgical resection with negative pathologic margins remains the treatment of choice.
in our knowledge, this is the first case of pancreatic GIST with pancreas divisum. Although pancreatic GISTs are uncommon tumours, they must be considered in the differential diagnosis of solid pancreatic lesions. Even though the tumour can be evaluated as high risk, treatment must be aggressive in order to improve survival rate.
胃肠道间质瘤（GISTs）是罕见的腹腔内肿瘤。这些肿瘤在胃和小肠中出现的频率往往更高。不到5%的病例主要起源于胃肠道外肿瘤（EGISTs）。胰腺胃肠道间质瘤非常罕见。仅有少数病例被报道。我们报告首例伴有胰腺分裂症的胰腺间质瘤病例。
一名39岁男性，表现为便秘和腹痛。计算机断层扫描显示胰腺有一个9厘米的肿块，无肝脏病变。成功实施了惠普尔手术及节段性结肠切除术。经过24个月的随访，患者情况良好，无疾病复发。
胰腺间叶性肿瘤极为罕见，占所有胰腺肿瘤的比例不到1%。内镜超声有助于诊断。手术切除且病理切缘阴性仍是首选治疗方法。
据我们所知，这是首例伴有胰腺分裂症的胰腺GIST病例。尽管胰腺GISTs是罕见肿瘤，但在胰腺实性病变的鉴别诊断中必须考虑到它们。即使肿瘤被评估为高危，也必须积极治疗以提高生存率。
