聚γ-（D）-谷氨酸胶囊会干扰炭疽杆菌特定噬菌体对炭疽杆菌的裂解感染。
Poly-γ-(D)-glutamic acid capsule interferes with lytic infection of Bacillus anthracis by B. anthracis-specific bacteriophages.
机构信息
University College London School of Pharmacy, London, United Kingdom.
出版信息
Appl Environ Microbiol. 2013 Jan;79(2):714-7. doi: 10.1128/AEM.02682-12. Epub 2012 Nov 2.
Abstract
The poly-γ-d-glutamic acid capsule of Bacillus anthracis is a barrier to infection by B. anthracis-specific bacteriophages. Capsule expression was found to completely inhibit lytic infection by γ phage, an observation supported by the demonstration that this phage does not elaborate a hydrolase that would facilitate penetration through the protective capsule outer layer.
摘要
炭疽杆菌的聚-γ-谷氨酸胶囊是炭疽杆菌特异性噬菌体感染的障碍。研究发现，胶囊表达完全抑制了γ噬菌体的裂解感染，这一观察结果得到了支持，证明这种噬菌体不产生有助于穿透保护性胶囊外层的水解酶。
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