细胞包膜：组成、生理作用及临床意义。
The Cell Envelope: Composition, Physiological Role, and Clinical Relevance.
作者信息
Chateau Alice, Van der Verren Sander E, Remaut Han, Fioravanti Antonella
机构信息
Avignon Université, INRAE, UMR SQPOV, F-84914 Avignon, France.
Structural and Molecular Microbiology, Structural Biology Research Center, VIB, 1050 Brussels, Belgium.
出版信息
Microorganisms. 2020 Nov 26;8(12):1864. doi: 10.3390/microorganisms8121864.
Anthrax is a highly resilient and deadly disease caused by the spore-forming bacterial pathogen . The bacterium presents a complex and dynamic composition of its cell envelope, which changes in response to developmental and environmental conditions and host-dependent signals. Because of their easy to access extracellular locations, cell envelope components represent interesting targets for the identification and development of novel therapeutic and vaccine strategies. This review will focus on the novel insights regarding the composition, physiological role, and clinical relevance of cell envelope components.
炭疽是一种由形成孢子的细菌病原体引起的极具韧性和致命性的疾病。这种细菌的细胞膜具有复杂且动态的组成，会根据发育、环境条件以及宿主相关信号而发生变化。由于细胞膜成分易于接触到细胞外区域，它们成为了识别和开发新型治疗与疫苗策略的有趣靶点。本综述将聚焦于关于细胞膜成分的组成、生理作用及临床相关性的新见解。
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