含芘季铵盐共聚物的合成及其与 DNA 杂交检测的荧光研究。
Synthesis and fluorescence study of a quaternized copolymer containing pyrene for DNA-hybridization detection.
机构信息
School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China.
出版信息
Chemphyschem. 2012 Dec 21;13(18):4099-104. doi: 10.1002/cphc.201200765. Epub 2012 Nov 5.
PMID:23129170
Abstract
Built-in detector: A quaternized copolymer containing pyrene is described, which can bind to single-stranded DNA by electrostatic interactions to form a novel complex probe for the detection of DNA hybridization through strengthened fluorescence quenching through its intercalation into double-stranded DNA (see figure).
摘要
内置探测器
本文描述了一种含有芘的季铵化共聚物，它可以通过静电相互作用与单链 DNA 结合，形成一种新型的复合物探针，通过其嵌入双链 DNA 来增强荧光猝灭，从而用于检测 DNA 杂交（见图）。
Zotero 插件