Department of Cardiology, University of Chicago, Chicago, IL, USA.
Pulm Circ. 2012 Jul;2(3):390-4. doi: 10.4103/2045-8932.101659.
Pulmonary arterial hypertension is a fatal disease. Intravenous prostanoids are often utilized for long-term management of patients. The therapy requires a significant commitment and change in lifestyle for both the patient and family. Takotsubo cardiomyopathy, transient apical ballooning syndrome, has been reported in association with emotional and physical stress. This case report describes a patient with pulmonary arterial hypertension who developed Takotsubo cardiomyopathy after treatment initiation with intravenous treprostinil. Over time, the syndrome resolved and the patient had return of normal left ventricular function. Takotsubo cardiomyopathy should be recognized as a potential, rare complication of therapy initiation due to the severity of the illness and the emotional stress of the disease.
肺动脉高压是一种致命的疾病。长期管理患者通常会使用静脉前列环素。这种治疗需要患者和家属在生活方式上做出重大改变和承诺。Takotsubo 心肌病，即短暂性心尖球囊综合征，与情绪和身体应激有关。本病例报告描述了一名肺动脉高压患者，在开始静脉注射曲前列尼尔治疗后出现 Takotsubo 心肌病。随着时间的推移，该综合征得到缓解，患者左心室功能恢复正常。Takotsubo 心肌病应被视为因疾病的严重程度和疾病的情绪压力而导致治疗开始时潜在的罕见并发症。
