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与梅尼埃病相关的良性阵发性位置性眩晕:流行病学、病理生理学、临床及治疗方面

Benign paroxysmal positional vertigo associated with Meniere's disease: epidemiological, pathophysiologic, clinical, and therapeutic aspects.

作者信息

Balatsouras Dimitrios G, Ganelis Panayotis, Aspris Andreas, Economou Nicolas C, Moukos Antonis, Koukoutsis George

机构信息

Department of Otolaryngology, Tzanion General Hospital, Piraeus, Greece.

出版信息

Ann Otol Rhinol Laryngol. 2012 Oct;121(10):682-8. doi: 10.1177/000348941212101011.

DOI:10.1177/000348941212101011
PMID:23130545
Abstract

OBJECTIVES

We studied the demographic, pathogenetic, and clinical features of benign paroxysmal positional vertigo (BPPV) associated with Meniere's disease.

METHODS

The medical records of patients with BPPV associated with Meniere's disease were reviewed. In all patients, results of a complete otolaryngological, audiological, and neurotologic evaluation, including nystagmography, were available. Patients with idiopathic BPPV were used as a control group.

RESULTS

Twenty-nine patients with both disorders were found and were compared with 233 patients with idiopathic BPPV. The patients with BPPV associated with Meniere's disease presented the following features, in which they differed from the patients with idiopathic BPPV: 1) a higher percentage of female patients; 2) a longer duration of symptoms; 3) common involvement of the horizontal semicircular canal; 4) a greater incidence of canal paresis; and 5) more therapeutic sessions needed for cure and a higher rate of recurrence.

CONCLUSIONS

The BPPV associated with Meniere's disease differs from idiopathic BPPV in regard to several epidemiological and clinical features, may follow a different course, and responds less effectively to treatment.

摘要

目的

我们研究了与梅尼埃病相关的良性阵发性位置性眩晕(BPPV)的人口统计学、发病机制和临床特征。

方法

回顾了与梅尼埃病相关的BPPV患者的病历。所有患者均有完整的耳鼻喉科、听力学和神经耳科学评估结果,包括眼震电图。特发性BPPV患者作为对照组。

结果

发现29例同时患有这两种疾病的患者,并与233例特发性BPPV患者进行比较。与梅尼埃病相关的BPPV患者具有以下与特发性BPPV患者不同的特征:1)女性患者比例更高;2)症状持续时间更长;3)水平半规管受累常见;4)管麻痹发生率更高;5)治愈所需治疗疗程更多且复发率更高。

结论

与梅尼埃病相关的BPPV在一些流行病学和临床特征方面与特发性BPPV不同,可能病程不同,对治疗的反应也较差。

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