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良性阵发性位置性眩晕与梅尼埃病综合征并存

Co-existence of Benign Paroxysmal Positional Vertigo and Meniere's Syndrome.

作者信息

Yetişer Sertaç

机构信息

Department of Otolaryngology, Anadolu Medical Center (Affl. Johns Hopkins Medicine), Kocaeli, Turkey.

出版信息

J Int Adv Otol. 2017 Apr;13(1):65-68. doi: 10.5152/iao.2016.2906. Epub 2017 Jan 13.

DOI:10.5152/iao.2016.2906
PMID:28085000
Abstract

OBJECTIVE

Recent studies indicate interrelation of benign paroxysmal positional vertigo (BPPV) and Meniere's disease (MD). These two entities may have different clinical characteristics.

MATERIALS AND METHODS

Five hundred thirty patients with BPPV evaluated between 2009-2015 were enrolled in the study. 351 patients who had no clear problem associated with BPPV (idiopathic) and 17 patients with MD were analyzed in detail. The age, sex, site of involvement, type of BPPV, symptom duration, and treatment outcome were compared.

RESULTS

Meniere's disease + BPPV was more common in the female population (2/15; 7.5 v 127/224; 1.8, p<0.05). Comparative analysis of average age was not statistically significant (42.82±9.94 v. 40.29±1.65, p=0.601). There was no difference in right and left ear involvement between groups. Lateral canal involvement was more common in the BPPV + MD group (9/17; 53% v. 100/351; 28%, p<0.05). BPPV was ipsilateral to the ear with MD in 75% of patients and it was present before the diagnosis of BPPV in 82.3% of patients. Comparative analysis of cure rate between idiopathic BPPV and BPPV + MD after one session was significant (64.7% v 78%, p<0.05).

CONCLUSION

Benign paroxysmal positional vertigo associated with MD presented a divergent picture. It was more frequent in females. Lateral canal involvement was higher. Patients had MD before the development of BPPV and they had prolonged symptoms, which raised a question of diagnostic delay since these two problems were in the same ear in majority of patients. Finally, relief of symptoms required more attempts of repositioning maneuvers.

摘要

目的

近期研究表明良性阵发性位置性眩晕(BPPV)与梅尼埃病(MD)之间存在关联。这两种疾病可能具有不同的临床特征。

材料与方法

本研究纳入了2009年至2015年间评估的530例BPPV患者。对351例无明确与BPPV相关问题(特发性)的患者和17例MD患者进行了详细分析。比较了年龄、性别、受累部位、BPPV类型、症状持续时间和治疗结果。

结果

梅尼埃病+BPPV在女性人群中更为常见(2/15;7.5对127/224;1.8,p<0.05)。平均年龄的比较分析无统计学意义(42.82±9.94对40.29±1.65,p=0.601)。两组之间左右耳受累情况无差异。水平半规管受累在BPPV+MD组中更为常见(9/17;53%对100/351;28%,p<0.05)。75%的患者BPPV与患MD的耳朵同侧,82.3%的患者在BPPV诊断之前就已存在MD。特发性BPPV和BPPV+MD一次治疗后的治愈率比较分析具有显著性(64.7%对78%,p<0.05)。

结论

与MD相关的良性阵发性位置性眩晕呈现出不同的情况。在女性中更为频繁。水平半规管受累更高。患者在BPPV发生之前就患有MD,且症状持续时间较长,由于这两个问题在大多数患者中位于同一耳,这就引发了诊断延迟的问题。最后,症状缓解需要更多次的复位手法尝试。

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