Yamasaki M, Akahori T, Mochizuki M, Kono M
Department of Obstetrics and Gynecology, Kobe University School of Medicine.
Nihon Sanka Fujinka Gakkai Zasshi. 1990 Feb;42(2):167-73.
Fifty-four patients with primary carcinoma of the cervix were examined by magnetic resonance imaging (MRI). Different pulse sequences with T1 and T2 weighting were employed to determine optimum tissue contrast. The tumor had a uniform signal intensity similar to the myometrium on the T1 weighted image. In contrast, the tumor signal intensity increased on the T2 weighted image. In our series the primary tumor was clearly defined in nine of twenty patients with stage 0 and I disease and thirty-three of thirty-four patients with stage II, III and IV disease. In addition, the primary tumor was clearly defined in four patients who had unsatisfactory colposcopic findings (UCF). Parametrial invasion of the tumor was well depicted on transverse planes in four of twelve sides with stage IIb disease and twenty-eight of thirty-four sides with stage III and IV disease. T1 weighted images provided excellent tissue contrast between the high signal from pelvic fat and the low intensity of tumor tissue enabling demonstration of involvement of the pelvic side wall. Vaginal invasion was also clearly seen on T2 weighted sagittal images in seventeen of twenty-six patients. In conclusion, MRI is not only useful but is also a non-invasive method of detecting primary tumor and extra-uterine extension of cervical carcinoma.
对54例子宫颈原发性癌患者进行了磁共振成像（MRI）检查。采用不同的T1和T2加权脉冲序列来确定最佳组织对比度。在T1加权图像上，肿瘤具有与子宫肌层相似的均匀信号强度。相比之下，在T2加权图像上肿瘤信号强度增加。在我们的系列研究中，20例0期和I期疾病患者中有9例以及34例II期、III期和IV期疾病患者中有33例的原发性肿瘤得到了清晰界定。此外，在4例阴道镜检查结果不满意（UCF）的患者中，原发性肿瘤也得到了清晰界定。在12例IIb期疾病患者的12个侧面中有4个以及34例III期和IV期疾病患者的34个侧面中有28个，肿瘤的宫旁浸润在横断面上得到了很好的显示。T1加权图像在盆腔脂肪的高信号与肿瘤组织的低信号之间提供了出色的组织对比度，能够显示盆腔侧壁受累情况。在26例患者中的17例，T2加权矢状位图像上也清晰可见阴道浸润。总之，MRI不仅有用，而且是检测子宫颈癌原发性肿瘤和子宫外扩展的一种非侵入性方法。
