[多药联合化疗与华氏巨球蛋白血症（作者译）]
[Polychimiotherapy and Waldenström's macroglobulinemia (author's transl)].
作者信息
Barrier J, Grolleau J Y, Renault J J, Ozanne P, Bouret O
出版信息
Sem Hop. 1979;55(41-42):1925-6.
PMID:231315
Abstract
A 63-year-old man, with a Waldenström's disease discovered by cryoglobulinemia (ischemic lesions of fingers) was quickly aggravating (hyperviscosity syndrome) under treatment by chlorambucil in a dosage of 8 mg daily. We obtained a dramatic remission with combination of cyclophosphamide, vincristine, adriamycin and prednisone surrounding a total body irradiation. A new trial of polychimiotherapy (with lower dosage) for severe Waldenström's disease is actually on study.
摘要
一名63岁男性，因冷球蛋白血症（手指缺血性病变）发现患有华氏巨球蛋白血症，在接受每日8毫克苯丁酸氮芥治疗时病情迅速加重（高黏滞综合征）。我们采用环磷酰胺、长春新碱、阿霉素和泼尼松联合全身照射，使病情得到显著缓解。目前正在进行一项针对重度华氏巨球蛋白血症的新的多药化疗试验（剂量较低）。
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