肥胖对非亲属活体供肾移植术后泌尿系统并发症的影响。
Impact of obesity on urologic complications among unrelated living donor kidney transplants.
作者信息
Kamali Koosha, Abbasi Mohammad Amin, Abbasi Ata, Mortazavi Ahmad, Seifee Mohammad Hasan
机构信息
Department of Urology, Hasheminezhad hospital, Iran University of Medical Science (IUMS), Tehran, Iran.
出版信息
Indian J Surg. 2010 Jun;72(3):211-4. doi: 10.1007/s12262-010-0055-y. Epub 2010 Aug 26.
PURPOSE
Although obesity has been associated with improved survival on dialysis, its effects on renal transplantation outcomes remain unclear. Herein we aimed to evaluate the effect of obesity on posttransplantation complications.
PATIENTS AND METHODS
A retrospective analysis of consecutive renal transplant recpients from un related living donors was undertaken from 2006 to 2008.
RESULTS
We included 180 patients, 34 (18%) were obese (body mass index >30 kg/m(2)) and 146 were lean. Obese patients were more likely to develope renal artery stenosis (17.6% vs 2.8%, p < 0.001), hematoma (47.9% vs 17.6, p = 0.009), wound complications (64.7% vs 9.6%, P < 0.001) and renal vein thrombosis(2% vs 0%, p < 0.001). Urologic complications consisting ureteral, ureteropelvic and ureterovesicular junction stenosis, wound bleeding, urinary leakage and renal artery thrombosis and also hospitalization time were found similar between the two groups. 2 year patiets and graft survival were not statististically different.
CONCLUSIONS
Renal transplantation could be performed with reasonable urologic complications in obese patients.
目的
尽管肥胖与透析患者生存率提高相关，但其对肾移植结局的影响仍不明确。在此，我们旨在评估肥胖对移植后并发症的影响。
患者与方法
对2006年至2008年来自非亲属活体供者的连续肾移植受者进行回顾性分析。
结果
我们纳入了180例患者，其中34例（18%）肥胖（体重指数>30 kg/m²），146例为瘦体型。肥胖患者更易发生肾动脉狭窄（17.6%对2.8%，p<0.001）、血肿（47.9%对17.6%，p = 0.009）、伤口并发症（64.7%对9.6%，P<0.001）和肾静脉血栓形成（2%对0%，p<0.001）。两组间泌尿系统并发症（包括输尿管、肾盂输尿管和输尿管膀胱连接部狭窄、伤口出血、尿漏和肾动脉血栓形成）以及住院时间相似。2年患者和移植物生存率无统计学差异。
结论
肥胖患者肾移植可在合理的泌尿系统并发症情况下进行。
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