Ilesanmi Olayinka Stephen, Ige Olusimbo Kehinde, Adebiyi Akindele Olupelumi
Department of Community Medicine, University College Hospital, Ibadan, Nigeria.
Pan Afr Med J. 2012;12:96. Epub 2012 Aug 6.
The health systems designed to cater for patients with chronic illnesses like hypertension have not fully evaluated the burden of long term therapy and its effect on patient outcome. This study assessed the financial implication and cost effectiveness of hypertension treatment in a rural Nigerian town.
A chart review of 250 rural patients with primary hypertension at a regional hospital in Southwest Nigeria was conducted.
The mean age of patients was 61 ± 11.2 years, 59.2% were females, 67% had an income < ₦20,000 ($133.3) monthly. Diuretics and alpha-Methyl Dopa were the most prescribed drugs. The median number of prescribed drugs was two (range1-4). Mean cost of treatment was ₦1440 ± 560 ($9.6 ± 3.7) with 52.8% spending ≥ 10% of their income on treatment. The most cost effective therapies were Methyl Dopa and Diuretics with Cost-effectiveness ratios of 8 and 12.8 respectively. Patients with co-morbidities, stage 2 hypertension and those on three or four drug regimen had significantly higher treatment costs.
The financial burden of long term antihypertensive therapy appears substantial, cost reduction strategies are needed to optimize hypertension treatment in societies with limited resources. Hypertensive management therefore requires a response adapted to the local context.
旨在照顾高血压等慢性病患者的卫生系统尚未充分评估长期治疗的负担及其对患者预后的影响。本研究评估了尼日利亚一个农村城镇高血压治疗的经济影响和成本效益。
对尼日利亚西南部一家地区医院的250名农村原发性高血压患者进行了病历审查。
患者的平均年龄为61±11.2岁,59.2%为女性,67%的月收入低于20,000奈拉(133.3美元)。利尿剂和α-甲基多巴是最常开具的药物。开具药物的中位数为两种(范围为1 - 4种)。平均治疗费用为1440±560奈拉(9.6±3.7美元),52.8%的患者将其收入的≥10%用于治疗。最具成本效益的治疗方法是甲基多巴和利尿剂,成本效益比分别为8和12.8。患有合并症、2期高血压以及接受三种或四种药物治疗方案的患者治疗成本显著更高。
长期抗高血压治疗的经济负担似乎很大,在资源有限的社会中需要采取成本降低策略来优化高血压治疗。因此,高血压管理需要因地制宜。