Acosta E
Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, UNAM, Mexico DF.
J Clin Lab Anal. 1990;4(2):90-4. doi: 10.1002/jcla.1860040204.
IgG antibodies to antigens of Taenia solium metacestodes were detected in saliva samples from patients with intracerebral cysticercosis by means of an enzyme-linked immunosorbent assay (ELISA). When compared for IgG antibody activity, saliva samples from patients with various nonparasitic neurological disorders and from clinically healthy individuals yielded significantly lower (p less than 0.001) absorbance values than saliva samples from patients with neurocysticercosis. However, no differences were observed in IgA anti-T. solium activity between patients with neurocysticercosis and controls. These results indicate that the detection of anticysticercus IgG antibodies in saliva by means of ELISA may be of value in the diagnosis of neurocysticercosis. Moreover, collection of saliva provides a noninvasive sampling method for immunoepidemiological surveys on this disease.
通过酶联免疫吸附测定（ELISA）在脑囊尾蚴病患者的唾液样本中检测到了针对猪带绦虫囊尾蚴抗原的IgG抗体。与各种非寄生虫性神经系统疾病患者以及临床健康个体的唾液样本相比，神经囊尾蚴病患者的唾液样本产生的吸光度值显著更低（p小于0.001）。然而，神经囊尾蚴病患者与对照之间在抗猪带绦虫IgA活性方面未观察到差异。这些结果表明，通过ELISA检测唾液中的抗囊尾蚴IgG抗体可能对神经囊尾蚴病的诊断有价值。此外，收集唾液为该疾病的免疫流行病学调查提供了一种非侵入性的采样方法。
