Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 710 North Lakeshore Drive, 7th Floor, Chicago, IL 60611, USA.
Ann Oncol. 2013 Apr;24(4):1073-8. doi: 10.1093/annonc/mds539. Epub 2012 Nov 7.
Health-related quality-of-life (HRQOL) assessments in research and clinical oncology settings are increasingly important. HRQOL instruments need to be rapid and still maintain the ability to capture the most relevant patient issues in a valid and reliable manner. The current study develops and validates the FACT-G7, a rapid version of the Functional Assessment of Cancer Therapy-General (FACT-G).
Oncology patients with advanced cancer (N = 533) from 11 diseases sites ranked the symptoms and concerns they viewed as 'the very most important' when undergoing cancer treatment, completed the FACT-G, and additional HRQOL measures. Oncology patients' scores were referenced across a general US population sample (N = 2000).
We selected the highest priority cancer-related symptoms and concerns endorsed by patients for inclusion in the FACT-G7. Fatigue and ability to enjoy life were ranked the most highly. The results provide preliminary support for the FACT-G7's internal consistency reliability (α = 0.74) and validity as evidenced by moderate-to-strong relationships with expected criteria. The references for the general population are summarized.
The FACT-G7 can be used to assess top-rated symptoms and concerns for a broad spectrum of advanced cancers in clinical practice and research.
在肿瘤学的研究和临床环境中，健康相关生活质量（HRQOL）的评估变得越来越重要。HRQOL 评估工具需要快速，同时仍能够以有效和可靠的方式捕捉到最相关的患者问题。本研究开发并验证了 FACT-G7，即功能性评估癌症治疗一般量表（FACT-G）的快速版本。
来自 11 个疾病部位的晚期癌症患者（N=533）对他们在接受癌症治疗时认为“最重要”的症状和关注点进行了排名，完成了 FACT-G 和其他 HRQOL 评估。患者的分数与一般美国人群样本（N=2000）进行了比较。
我们选择了患者最认可的最高优先级的癌症相关症状和关注点纳入 FACT-G7。疲劳和享受生活的能力排名最高。结果初步支持了 FACT-G7 的内部一致性可靠性（α=0.74）和有效性，这体现在与预期标准的中度至强相关关系上。还总结了一般人群的参考分数。
FACT-G7 可用于在临床实践和研究中评估广泛的晚期癌症患者的高评级症状和关注点。
