Christ M L, Haja J
Acta Cytol. 1979 Jul-Aug;23(4):327-31.
In order to determine the frequency and specificity of intranuclear cytoplasmic inclusions (invaginations), described by some as an important criterion for the cytologic diagnosis of thyroid carcinoma, 258 consecutive thyroid aspirates were reviewed. Intranuclear cytoplasmic inclusions were present in 91% of the papillary adenocarcinomas but were not seen in any of the benign thyroid lesions or in any of the few nonpapillary adenocarcinomas in the study. It is concluded that the presence of intranuclear cytoplasmic inclusions in thyroid aspirates is probably specific to thyroid carcinoma but is not necessarily restricted to the papillary variant.
为了确定核内胞质包涵体（内陷）的出现频率和特异性，一些人将其描述为甲状腺癌细胞学诊断的重要标准，我们回顾了258例连续的甲状腺穿刺样本。核内胞质包涵体存在于91%的乳头状腺癌中，但在本研究的任何良性甲状腺病变或少数非乳头状腺癌中均未见到。结论是，甲状腺穿刺样本中核内胞质包涵体的存在可能是甲状腺癌所特有的，但不一定局限于乳头状变体。
