Mantri Sneha S, Parkhedkar Rambhau D, Mantri Shivkumar P
Departmentt of Prosthodontics, Hitkarini Dental College & Hospital, Jabalpur, India.
Gerodontology. 2013 Dec;30(4):288-95. doi: 10.1111/ger.12012. Epub 2012 Nov 9.
The aim of this study was to evaluate Candida colonisation in the dentures with silicone soft liner in diabetic and non-diabetic patients and to assess the antifungal efficacy of chlorhexidine gluconate on Candida colonies.
Thirty patients with resorbed ridges, fifteen each in the diabetic and non-diabetic group, were selected. The mandibular denture of each patient was lined with heat-polymerised silicone resilient liner. Patients were instructed to clean the dentures with soap water and brush. Samples from the fitting surface of mandibular dentures were collected at 15, 21 and 30 days. Subsequently, samples were collected at 15, 21 and 30 days, after cleaning the dentures with a detergent solution of 4% chlorhexidine gluconate, and incubated for the evaluation of Candida growth. These data were subjected to statistical analysis by Mann-Whitney U-test.
Normal oral flora in diabetics and non-diabetics showed no difference (p > 0.05). The density of colonies increased after 21 and 30 days in diabetic patients (p < 0.05). Number of Candida colonies significantly reduced in both the groups after 21 and 30 days of cleaning the dentures with 4% chlorhexidine gluconate (p < 0.05).
Dentures with silicone resilient liner exhibit increased Candida growth in diabetic patients. Four per cent chlorhexidine gluconate solution effectively disinfects these dentures.
本研究旨在评估糖尿病患者和非糖尿病患者使用含硅橡胶软衬垫的义齿中的念珠菌定植情况，并评估葡萄糖酸氯己定对念珠菌菌落的抗真菌效果。
选取30例牙槽嵴吸收患者，糖尿病组和非糖尿病组各15例。为每位患者的下颌义齿衬以热聚合硅橡胶弹性衬垫。指导患者用肥皂水和牙刷清洁义齿。在第15、21和30天从下颌义齿的贴合面采集样本。随后，在用4%葡萄糖酸氯己定洗涤剂溶液清洁义齿后的第15、21和30天采集样本，并进行培养以评估念珠菌生长情况。这些数据采用曼-惠特尼U检验进行统计分析。
糖尿病患者和非糖尿病患者的正常口腔菌群无差异（p>0.05）。糖尿病患者在21天和30天后菌落密度增加（p<0.05）。在用4%葡萄糖酸氯己定清洁义齿21天和30天后，两组的念珠菌菌落数量均显著减少（p<0.05）。
含硅橡胶弹性衬垫的义齿在糖尿病患者中念珠菌生长增加。4%葡萄糖酸氯己定溶液可有效对这些义齿进行消毒。
Zotero 插件